Trends in AI and Human-AI Interaction in Clinical Trials -- A Hybrid Human-AI Exploration

In three linesAnalysis of ClinicalTrials.gov registry shows marked increase in AI-related trials over time, with recent growth in machine learning, deep learning, chatbots, GPTs, and LLMs. China and US lead geographically. Hybrid approach using GPT-5.5 and human review: good agreement on non-AI studies, lower agreement on human-AI interaction classification.

Summary generated by Claude — human-verified